Curcumin glucuronides: Assessing the proliferative activity against human cell lines
نویسندگان
چکیده
منابع مشابه
Cytotoxicity of Curcumin against Leukemic Cell Lines via Apoptosis Activity
The aimed of this study was to evaluate curcumin as anticancer agent. The apoptogenic and Cytotoxic activity of curcumin were investigated against two human leukemic cell lines-U937 and Molt4. Cytotoxic activity was performed by using [3-[4, 5-dimethylthiazol-2yl] 2, 5 diphenyltetrazolium bromide] MTT assay. Also 4, 6-diamidino-2-phenylindole di-hydrochloride [DAPI] staining was used as a DNA-b...
متن کاملCurcumin inhibits telomerase activity in human cancer cell lines.
Curcumin, one of the major components of tumeric, the dried rhizome of Curcuma longa L, has been shown to have anti-proliferating and anti-carcinogenic properties. In this study, we examined the effects of curcumin on cell growth and telomerase activity in human cancer cell lines Bel7402, HL60 and SGC7901. Curcumin (1-32 microM) showed anti-proliferating effects on these cell lines in a dose-de...
متن کاملCytotoxic activity of styrylchromones against human tumor cell lines.
A total of 6 newly-synthesized styrylchromones (SC-1 approximately SC-6) were compared for their cytotoxic activity against three normal oral human cells (gingival fibroblast HGF, pulp cell HPC, periodontal ligament fibroblast HPLF) and four human tumor cell lines (squamous cell carcinoma HSC-2, HSC-3, submandibular gland carcinoma HSG, promyelocytic leukemia HL-60). All compounds showed higher...
متن کاملCytotoxic activity of azulenequinones against human oral tumor cell lines.
We investigated twenty-seven azulenequinone derivatives for their relative cytotoxicity against three human normal cell lines (HGF, HPC, HPLF) and four human tumor cell lines (HSG, HSC-2, HSC-3, HL-60). Parent 1,5-azulenequinone showed potent and some tumor-specific cytotoxicity. Halogenated derivatives of 1,5- and 1,7-azulenequinone showed potent cytotoxicity, but lower tumor-specific cytotoxi...
متن کاملAnti-proliferative and apoptosis-inducing activity of lycopene against three subtypes of human breast cancer cell lines
Although lycopene, a major carotenoid component of tomatoes, has been suggested to attenuate the risk of breast cancer, the underlying preventive mechanism remains to be determined. Moreover, it is not known whether there are any differences in lycopene activity among different subtypes of human breast cancer cells. Using ER/PR positive MCF-7, HER2-positive SK-BR-3 and triple-negative MDA-MB-46...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry
سال: 2014
ISSN: 0968-0896
DOI: 10.1016/j.bmc.2013.11.006